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Mitochondrial thioredoxin reductase 2 is elevated in long‐lived primate as well as rodent species and extends fly mean lifespan

In a survey of enzymes related to protein oxidation and cellular redox state, we found activity of the redox enzyme thioredoxin reductase (TXNRD) to be elevated in cells from long‐lived species of rodents, primates, and birds. Elevated TXNRD activity in long‐lived species reflected increases in the...

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Detalles Bibliográficos
Autores principales: Pickering, Andrew M., Lehr, Marcus, Gendron, Christi M., Pletcher, Scott D., Miller, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506402/
https://www.ncbi.nlm.nih.gov/pubmed/28474396
http://dx.doi.org/10.1111/acel.12596