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Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health

Older adults universally suffer from sarcopenia and approximately 60–70% are diabetic or prediabetic. Nonetheless, the mechanisms underlying these aging‐related metabolic disorders are unknown. NFκB has been implicated in the pathogenesis of several aging‐related pathologies including sarcopenia and...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Valentine, Joseph M., Zhou, You, Li, Mengyao E., Zhang, Yiqiang, Bhattacharya, Arunabh, Walsh, Michael E., Fischer, Katherine E., Austad, Steven N., Osmulski, Pawel, Gaczynska, Maria, Shoelson, Steven E., Van Remmen, Holly, Chen, Hung I., Chen, Yidong, Liang, Hanyu, Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506420/
https://www.ncbi.nlm.nih.gov/pubmed/28556540
http://dx.doi.org/10.1111/acel.12613