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Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health
Older adults universally suffer from sarcopenia and approximately 60–70% are diabetic or prediabetic. Nonetheless, the mechanisms underlying these aging‐related metabolic disorders are unknown. NFκB has been implicated in the pathogenesis of several aging‐related pathologies including sarcopenia and...
Autores principales: | Zhang, Ning, Valentine, Joseph M., Zhou, You, Li, Mengyao E., Zhang, Yiqiang, Bhattacharya, Arunabh, Walsh, Michael E., Fischer, Katherine E., Austad, Steven N., Osmulski, Pawel, Gaczynska, Maria, Shoelson, Steven E., Van Remmen, Holly, Chen, Hung I., Chen, Yidong, Liang, Hanyu, Musi, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506420/ https://www.ncbi.nlm.nih.gov/pubmed/28556540 http://dx.doi.org/10.1111/acel.12613 |
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