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Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner
Aging leads to hypothalamic inflammation, but does so more slowly in mice whose lifespan has been extended by mutations that affect GH/IGF‐1 signals. Early‐life exposure to GH by injection, or to nutrient restriction in the first 3 weeks of life, also modulate both lifespan and the pace of hypothala...
Autores principales: | Sadagurski, Marianna, Cady, Gillian, Miller, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506421/ https://www.ncbi.nlm.nih.gov/pubmed/28544365 http://dx.doi.org/10.1111/acel.12590 |
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