Transcription factors CEP‐1/p53 and CEH‐23 collaborate with AAK‐2/AMPK to modulate longevity in Caenorhabditis elegans.

A decline in mitochondrial electron transport chain (ETC) function has long been implicated in aging and various diseases. Recently, moderate mitochondrial ETC dysfunction has been found to prolong lifespan in diverse organisms, suggesting a conserved and complex role of mitochondria in longevity de...

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Detalles Bibliográficos
Autores principales: Chang, Hsin‐Wen, Pisano, Steve, Chaturbedi, Amaresh, Chen, Jennifer, Gordon, Sarah, Baruah, Aiswarya, Lee, Siu Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506430/
https://www.ncbi.nlm.nih.gov/pubmed/28560849
http://dx.doi.org/10.1111/acel.12619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506430/
https://www.ncbi.nlm.nih.gov/pubmed/28560849
http://dx.doi.org/10.1111/acel.12619

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