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Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses

Horses have substantial variation in coat color, and the genetic loci responsible for the coat color variations have been well investigated. It has been believed that some color variations should follow a single-locus Mendelian law. Examples include the Gray locus that causes the gray phenotype and...

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Autores principales: SAKAMOTO, Takahiro, FAWCETT, Jeffrey A., INNAN, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Equine Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506451/
https://www.ncbi.nlm.nih.gov/pubmed/28721125
http://dx.doi.org/10.1294/jes.28.61
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author SAKAMOTO, Takahiro
FAWCETT, Jeffrey A.
INNAN, Hideki
author_facet SAKAMOTO, Takahiro
FAWCETT, Jeffrey A.
INNAN, Hideki
author_sort SAKAMOTO, Takahiro
collection PubMed
description Horses have substantial variation in coat color, and the genetic loci responsible for the coat color variations have been well investigated. It has been believed that some color variations should follow a single-locus Mendelian law. Examples include the Gray locus that causes the gray phenotype and the Extension locus that specifies the chestnut phenotype. We reevaluated the roles of the Gray and Extension loci by using a large number of mating records of Thoroughbred racing horses. We showed that the data indeed fits the Mendelian law extremely well for the two loci. Furthermore, we demonstrated that the Extension and Agouti loci might have an additional role in determining the degree of melanin that should distinguish bay, dark bay, and brown.
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spelling pubmed-55064512017-07-18 Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses SAKAMOTO, Takahiro FAWCETT, Jeffrey A. INNAN, Hideki J Equine Sci Note Horses have substantial variation in coat color, and the genetic loci responsible for the coat color variations have been well investigated. It has been believed that some color variations should follow a single-locus Mendelian law. Examples include the Gray locus that causes the gray phenotype and the Extension locus that specifies the chestnut phenotype. We reevaluated the roles of the Gray and Extension loci by using a large number of mating records of Thoroughbred racing horses. We showed that the data indeed fits the Mendelian law extremely well for the two loci. Furthermore, we demonstrated that the Extension and Agouti loci might have an additional role in determining the degree of melanin that should distinguish bay, dark bay, and brown. The Japanese Society of Equine Science 2017-07-06 2017 /pmc/articles/PMC5506451/ /pubmed/28721125 http://dx.doi.org/10.1294/jes.28.61 Text en 2017 The Japanese Society of Equine Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Note
SAKAMOTO, Takahiro
FAWCETT, Jeffrey A.
INNAN, Hideki
Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title_full Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title_fullStr Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title_full_unstemmed Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title_short Evaluating the potential roles of the Gray and Extension loci in the coat coloration of Thoroughbred racing horses
title_sort evaluating the potential roles of the gray and extension loci in the coat coloration of thoroughbred racing horses
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506451/
https://www.ncbi.nlm.nih.gov/pubmed/28721125
http://dx.doi.org/10.1294/jes.28.61
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