Cargando…
Diabetic rats present higher urinary loss of proteins and lower renal expression of megalin, cubilin, ClC‐5, and CFTR
Diabetic nephropathy (DN) occurs in around 40% of those with diabetes. Proteinuria is the main characteristic of DN and develops as a result of increased permeability of the glomerulus capillary wall and/or decreased proximal tubule endocytosis. The goal of this work was to evaluate renal function a...
Autores principales: | Figueira, Miriam F., Castiglione, Raquel C., de Lemos Barbosa, Carolina M., Ornellas, Felipe M., da Silva Feltran, Geórgia, Morales, Marcelo M., da Fonseca, Rodrigo N., de Souza‐Menezes, Jackson |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506523/ https://www.ncbi.nlm.nih.gov/pubmed/28676554 http://dx.doi.org/10.14814/phy2.13335 |
Ejemplares similares
-
Proximal Tubular Expression Patterns of Megalin and Cubilin in Proteinuric Nephropathies
por: Sun, Jia, et al.
Publicado: (2017) -
Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells
por: Rbaibi, Youssef, et al.
Publicado: (2023) -
Microalbuminuria in Type 1 Diabetes Is Associated With Enhanced Excretion of the Endocytic Multiligand Receptors Megalin and Cubilin
por: Thrailkill, Kathryn M., et al.
Publicado: (2009) -
Lack of megalin expression in adult human terminal ileum suggests megalin‐independent cubilin/amnionless activity during vitamin B(12) absorption
por: Jensen, Louise L., et al.
Publicado: (2014) -
Expression and immunolocalisation of the endocytic receptors megalin and cubilin in the human yolk sac and placenta across gestation()
por: Burke, K.A., et al.
Publicado: (2013)