Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

BACKGROUND: Mesenchymal stem cells (MSCs) attenuate lung injury in experimental models of bronchopulmonary dysplasia (BPD). Stromal derived factor-1 (SDF-1), a chemokine secreted by MSCs, modulates angiogenesis and stem cell recruitment. Here we tested the hypothesis that SDF-1 mediates MSC protecti...

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Detalles Bibliográficos
Autores principales: Reiter, Joel, Drummond, Shelley, Sammour, Ibrahim, Huang, Jian, Florea, Victoria, Dornas, Polliana, Hare, Joshua M., Rodrigues, Claudia O., Young, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506612/
https://www.ncbi.nlm.nih.gov/pubmed/28701189
http://dx.doi.org/10.1186/s12931-017-0620-z

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