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Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia

BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies. A new regimen to treat MDR-TB that includes pyrazinamide (PZA) is currently being evaluated and PZA resistance status will largely influence the success...

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Detalles Bibliográficos
Autores principales:	Sengstake, Sarah, Bergval, Indra L, Schuitema, Anja R, de Beer, Jessica L, Phelan, Jody, de Zwaan, Rina, Clark, Taane G, van Soolingen, Dick, Anthony, Richard M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506614/ https://www.ncbi.nlm.nih.gov/pubmed/28697808 http://dx.doi.org/10.1186/s12879-017-2594-3

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