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Formulation and pharmacokinetics of multi-layered matrix tablets: Biphasic delivery of diclofenac
The rapid availability of the drug at the site of action followed by maintaining its effect for a long period of time is of great clinical importance. Thus, the purpose of the present study was to prepare and evaluate multi-layered matrix tablets of diclofenac using Eudragit RL/RS blend to achieve b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506666/ https://www.ncbi.nlm.nih.gov/pubmed/28725140 http://dx.doi.org/10.1016/j.jsps.2016.10.004 |