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New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities
Panax ginseng C. A. Meyer (Araliaceae), is a well-known herb and used in the old established system of Oriental remedy, especially in Japan, China and Korea. Four new compounds characterized as (cis)- 7β,11α,19,21-tetra-O-decanoyl-18, 22β-dihydroxy-dammar-1-en-3-one (1), 3β,4α,12β-trihydroxystigmast...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506737/ https://www.ncbi.nlm.nih.gov/pubmed/28725154 http://dx.doi.org/10.1016/j.jsps.2016.12.002 |
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author | Chung, Ill-Min Siddiqui, Nasir Ali Kim, Seung Hyun Nagella, Praveen Khan, Azmat Ali Ali, Mohd Ahmad, Ateeque |
author_facet | Chung, Ill-Min Siddiqui, Nasir Ali Kim, Seung Hyun Nagella, Praveen Khan, Azmat Ali Ali, Mohd Ahmad, Ateeque |
author_sort | Chung, Ill-Min |
collection | PubMed |
description | Panax ginseng C. A. Meyer (Araliaceae), is a well-known herb and used in the old established system of Oriental remedy, especially in Japan, China and Korea. Four new compounds characterized as (cis)- 7β,11α,19,21-tetra-O-decanoyl-18, 22β-dihydroxy-dammar-1-en-3-one (1), 3β,4α,12β-trihydroxystigmast-5-en-21-yl octadecan-9′,12′-dienoate (2), dammar-12, 24-dien-3α, 6β, 15α-triol-3α-D-arabinopyranosyl-6β-L-arabinopyranoside (3) and dammar-24-en-3α, 6β, 16α, 20β-tetraol-3α-D-arabinopyranosyl-6β-D-arabinopyranoside (4) were isolated and established from the ethyl acetate and butanol extracts of the roots of P. ginseng. Their structures were established on the basis of spectral data and chemical reactions. Natural compounds indicative a great reservoir of materials and compounds with evolved biological activity, including antioxidant. Compounds 1–4 were investigated in vitro for antioxidant potential using ferric reducing antioxidant power (FRAP), the Nitric oxide (NO) scavenging activity, reducing power, phosphomolybdenum and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging actions, and the decision showed the compounds 3and 4 have probablyessential antioxidant properties than the compounds 1and 2 presented weak activity. |
format | Online Article Text |
id | pubmed-5506737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-55067372017-07-19 New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities Chung, Ill-Min Siddiqui, Nasir Ali Kim, Seung Hyun Nagella, Praveen Khan, Azmat Ali Ali, Mohd Ahmad, Ateeque Saudi Pharm J Original Article Panax ginseng C. A. Meyer (Araliaceae), is a well-known herb and used in the old established system of Oriental remedy, especially in Japan, China and Korea. Four new compounds characterized as (cis)- 7β,11α,19,21-tetra-O-decanoyl-18, 22β-dihydroxy-dammar-1-en-3-one (1), 3β,4α,12β-trihydroxystigmast-5-en-21-yl octadecan-9′,12′-dienoate (2), dammar-12, 24-dien-3α, 6β, 15α-triol-3α-D-arabinopyranosyl-6β-L-arabinopyranoside (3) and dammar-24-en-3α, 6β, 16α, 20β-tetraol-3α-D-arabinopyranosyl-6β-D-arabinopyranoside (4) were isolated and established from the ethyl acetate and butanol extracts of the roots of P. ginseng. Their structures were established on the basis of spectral data and chemical reactions. Natural compounds indicative a great reservoir of materials and compounds with evolved biological activity, including antioxidant. Compounds 1–4 were investigated in vitro for antioxidant potential using ferric reducing antioxidant power (FRAP), the Nitric oxide (NO) scavenging activity, reducing power, phosphomolybdenum and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging actions, and the decision showed the compounds 3and 4 have probablyessential antioxidant properties than the compounds 1and 2 presented weak activity. Elsevier 2017-07 2016-12-24 /pmc/articles/PMC5506737/ /pubmed/28725154 http://dx.doi.org/10.1016/j.jsps.2016.12.002 Text en © 2016 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Chung, Ill-Min Siddiqui, Nasir Ali Kim, Seung Hyun Nagella, Praveen Khan, Azmat Ali Ali, Mohd Ahmad, Ateeque New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title | New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title_full | New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title_fullStr | New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title_full_unstemmed | New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title_short | New constituents triterpene ester and sugar derivatives from Panax ginseng Meyer and their evaluation of antioxidant activities |
title_sort | new constituents triterpene ester and sugar derivatives from panax ginseng meyer and their evaluation of antioxidant activities |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506737/ https://www.ncbi.nlm.nih.gov/pubmed/28725154 http://dx.doi.org/10.1016/j.jsps.2016.12.002 |
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