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A phase 2 study of radiosurgery and temozolomide for patients with 1 to 4 brain metastases

PURPOSE: To determine if temozolomide reduces the risk of distant brain failure (DBF, metachronous brain metastases) in patients with 1 to 4 brain metastases treated with radiosurgery without whole-brain radiation therapy (WBRT). METHODS AND MATERIALS: Twenty-five patients with newly diagnosed brain...

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Detalles Bibliográficos
Autores principales: Fiveash, John B., Arafat, Waleed O., Naoum, George E., Guthrie, Barton L., Sawrie, Stephen M., Spencer, Sharon A., Meredith, Ruby F., Markert, James M., Conry, Robert M., Nabors, Burt L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506740/
https://www.ncbi.nlm.nih.gov/pubmed/28740873
http://dx.doi.org/10.1016/j.adro.2016.03.004