Increased urinary prostaglandin E2 metabolite: A potential therapeutic target of Gitelman syndrome

BACKGROUND: Gitelman syndrome (GS), an inherited autosomal recessive salt-losing renal tubulopathy caused by mutations in SLC12A3 gene, has been associated with normal prostaglandin E2 (PGE2) levels since 1995 by a study involving 11 clinically diagnosed patients. However, it is difficult to explain...

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Detalles Bibliográficos
Autores principales: Peng, Xiaoyan, Jiang, Lanping, Chen, Chen, Qin, Yan, Yuan, Tao, Wang, Ou, Xing, Xiaoping, Li, Xuemei, Nie, Min, Chen, Limeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507263/
https://www.ncbi.nlm.nih.gov/pubmed/28700713
http://dx.doi.org/10.1371/journal.pone.0180811

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