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Protocols to Study Aging in Drosophila

The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes c...

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Autores principales: Piper, Matthew D. W., Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer New York 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507281/
https://www.ncbi.nlm.nih.gov/pubmed/27730590
http://dx.doi.org/10.1007/978-1-4939-6371-3_18
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author Piper, Matthew D. W.
Partridge, Linda
author_facet Piper, Matthew D. W.
Partridge, Linda
author_sort Piper, Matthew D. W.
collection PubMed
description The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.
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spelling pubmed-55072812017-07-12 Protocols to Study Aging in Drosophila Piper, Matthew D. W. Partridge, Linda Methods Mol Biol Article The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet. Springer New York 2016-10-12 /pmc/articles/PMC5507281/ /pubmed/27730590 http://dx.doi.org/10.1007/978-1-4939-6371-3_18 Text en © The Author(s) 2016 Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.The images or other third party material in this chapter are included in the chapter’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the chapter’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
spellingShingle Article
Piper, Matthew D. W.
Partridge, Linda
Protocols to Study Aging in Drosophila
title Protocols to Study Aging in Drosophila
title_full Protocols to Study Aging in Drosophila
title_fullStr Protocols to Study Aging in Drosophila
title_full_unstemmed Protocols to Study Aging in Drosophila
title_short Protocols to Study Aging in Drosophila
title_sort protocols to study aging in drosophila
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507281/
https://www.ncbi.nlm.nih.gov/pubmed/27730590
http://dx.doi.org/10.1007/978-1-4939-6371-3_18
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