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Protocols to Study Aging in Drosophila
The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes c...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer New York
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507281/ https://www.ncbi.nlm.nih.gov/pubmed/27730590 http://dx.doi.org/10.1007/978-1-4939-6371-3_18 |
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author | Piper, Matthew D. W. Partridge, Linda |
author_facet | Piper, Matthew D. W. Partridge, Linda |
author_sort | Piper, Matthew D. W. |
collection | PubMed |
description | The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet. |
format | Online Article Text |
id | pubmed-5507281 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer New York |
record_format | MEDLINE/PubMed |
spelling | pubmed-55072812017-07-12 Protocols to Study Aging in Drosophila Piper, Matthew D. W. Partridge, Linda Methods Mol Biol Article The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet. Springer New York 2016-10-12 /pmc/articles/PMC5507281/ /pubmed/27730590 http://dx.doi.org/10.1007/978-1-4939-6371-3_18 Text en © The Author(s) 2016 Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.The images or other third party material in this chapter are included in the chapter’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the chapter’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. |
spellingShingle | Article Piper, Matthew D. W. Partridge, Linda Protocols to Study Aging in Drosophila |
title | Protocols to Study Aging in Drosophila |
title_full | Protocols to Study Aging in Drosophila |
title_fullStr | Protocols to Study Aging in Drosophila |
title_full_unstemmed | Protocols to Study Aging in Drosophila |
title_short | Protocols to Study Aging in Drosophila |
title_sort | protocols to study aging in drosophila |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507281/ https://www.ncbi.nlm.nih.gov/pubmed/27730590 http://dx.doi.org/10.1007/978-1-4939-6371-3_18 |
work_keys_str_mv | AT pipermatthewdw protocolstostudyagingindrosophila AT partridgelinda protocolstostudyagingindrosophila |