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Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt
The combination of irradiated fibroblast feeder cells and Rho kinase inhibitor, Y-267362, converts primary epithelial cells growing in vitro into an undifferentiated adult stem cell-like state that is characterized by long-term proliferation. This cell culture method also maintains the proliferation...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507294/ https://www.ncbi.nlm.nih.gov/pubmed/28700668 http://dx.doi.org/10.1371/journal.pone.0180897 |