Polymorphisms in the vitamin D receptor gene are associated with reduced rate of sputum culture conversion in multidrug-resistant tuberculosis patients in South Africa

BACKGROUND: Vitamin D modulates the inflammatory and immune response to tuberculosis (TB) and also mediates the induction of the antimicrobial peptide cathelicidin. Deficiency of 25-hydroxyvitamin D and single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene may increase the risk...

Descripción completa

Detalles Bibliográficos
Autores principales: Magee, Matthew J., Sun, Yan V., Brust, James C. M., Shah, N. Sarita, Ning, Yuming, Allana, Salim, Campbell, Angela, Hui, Qin, Mlisana, Koleka, Moodley, Pravi, Gandhi, Neel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507304/
https://www.ncbi.nlm.nih.gov/pubmed/28700743
http://dx.doi.org/10.1371/journal.pone.0180916

Ejemplares similares

Ejemplares similares