Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy

BACKGROUND & AIMS: The autoimmune hepatitis (AIH) is a chronic hepatitis driven by the adaptive immunity that affects all age groups. A functional and numerical regulatory T cell (Treg) defect has been reported in pediatric AIH (pAIH), while an intrahepatic increase in adult AIH (aAIH) patients...

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Detalles Bibliográficos
Autores principales: Diestelhorst, Jana, Junge, Norman, Schlue, Jerome, Falk, Christine S., Manns, Michael P., Baumann, Ulrich, Jaeckel, Elmar, Taubert, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507441/
https://www.ncbi.nlm.nih.gov/pubmed/28700730
http://dx.doi.org/10.1371/journal.pone.0181107

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