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Gallic acid/hydroxypropyl-β-cyclodextrin complex: Improving solubility for application on in vitro/ in vivo Candida albicans biofilms
The aim of this study was to increase the solubility of gallic acid (GA) for the treatment of Candida albicans biofilm, which is very difficult to treat and requires high drug concentrations. Cyclodextrins (CDs) were used for this purpose. Complexes were evaluated by phase-solubility studies, prepar...
Autores principales: | Teodoro, Guilherme Rodrigues, Gontijo, Aline Vidal Lacerda, Borges, Aline Chiodi, Tanaka, Márcia Hiromi, Lima, Gabriela de Morais Gouvêa, Salvador, Marcos José, Koga-Ito, Cristiane Yumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507443/ https://www.ncbi.nlm.nih.gov/pubmed/28700692 http://dx.doi.org/10.1371/journal.pone.0181199 |
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