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Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species
The pathogenic fungus Candida glabrata is often resistant to azole antifungal agents. Drug efflux through azole transporters, such as Cdr1 and Cdr2, is a key mechanism of azole resistance and these genes are under the control of the transcription factor Pdr1. Recently, the monoamine oxidase A (MAO-A...
Autores principales: | Nagayoshi, Yohsuke, Miyazaki, Taiga, Shimamura, Shintaro, Nakayama, Hironobu, Minematsu, Asuka, Yamauchi, Shunsuke, Takazono, Takahiro, Nakamura, Shigeki, Yanagihara, Katsunori, Kohno, Shigeru, Mukae, Hiroshi, Izumikawa, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507446/ https://www.ncbi.nlm.nih.gov/pubmed/28700656 http://dx.doi.org/10.1371/journal.pone.0180990 |
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