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The quantitative impact of read mapping to non-native reference genomes in comparative RNA-Seq studies

Sequence read alignment to a reference genome is a fundamental step in many genomics studies. Accuracy in this fundamental step is crucial for correct interpretation of biological data. In cases where two or more closely related bacterial strains are being studied, a common approach is to simply map...

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Detalles Bibliográficos
Autores principales: Price, Adam, Gibas, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507458/
https://www.ncbi.nlm.nih.gov/pubmed/28700635
http://dx.doi.org/10.1371/journal.pone.0180904