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The quantitative impact of read mapping to non-native reference genomes in comparative RNA-Seq studies
Sequence read alignment to a reference genome is a fundamental step in many genomics studies. Accuracy in this fundamental step is crucial for correct interpretation of biological data. In cases where two or more closely related bacterial strains are being studied, a common approach is to simply map...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507458/ https://www.ncbi.nlm.nih.gov/pubmed/28700635 http://dx.doi.org/10.1371/journal.pone.0180904 |