ANK1 is up-regulated in laser captured microglia in Alzheimer’s brain; the importance of addressing cellular heterogeneity

Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer’s disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because of the range of cell types analyzed. In order to ad...

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Detalles Bibliográficos
Autores principales: Mastroeni, Diego, Sekar, Shobana, Nolz, Jennifer, Delvaux, Elaine, Lunnon, Katie, Mill, Jonathan, Liang, Winnie S., Coleman, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507536/
https://www.ncbi.nlm.nih.gov/pubmed/28700589
http://dx.doi.org/10.1371/journal.pone.0177814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507536/
https://www.ncbi.nlm.nih.gov/pubmed/28700589
http://dx.doi.org/10.1371/journal.pone.0177814

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