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Apoptosis by [Pt(O,O′-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma

Mesothelioma cancer cells have epithelioid or sarcomatoid morphology. The worst prognosis is associated with sarcomatoid phenotype and resistance to therapy is affected by cells heterogeneity. We recently showed that in ZL55 mesothelioma cell line of epithelioid origin [Pt(O,O′-acac)(γ-acac)(DMS)] (...

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Detalles Bibliográficos
Autores principales:	Muscella, Antonella, Vetrugno, Carla, Cossa, Luca Giulio, Antonaci, Giovanna, Barca, Amilcare, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507537/ https://www.ncbi.nlm.nih.gov/pubmed/28704484 http://dx.doi.org/10.1371/journal.pone.0181114

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