A second reported malignancy in a patient with Morquio syndrome

Morquio syndrome is a rare lysosomal storage disease that affects multiple organ systems. However, it is rarely associated with malignancy. We present the case of a 30-year old man with Morquio syndrome associated with gastric adenocarcinoma. This case also demonstrates two other findings that have...

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Detalles Bibliográficos
Autores principales: Hamza, Ameer, Khawar, Sidrah, Ibrahim, Ahmad, Edens, Jacob, Lalonde, Crystal, Danforth, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017
Materias:
Article / Autopsy Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507564/
https://www.ncbi.nlm.nih.gov/pubmed/28740834
http://dx.doi.org/10.4322/acr.2017.019
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author Hamza, Ameer
Khawar, Sidrah
Ibrahim, Ahmad
Edens, Jacob
Lalonde, Crystal
Danforth, Robert D.
author_facet Hamza, Ameer
Khawar, Sidrah
Ibrahim, Ahmad
Edens, Jacob
Lalonde, Crystal
Danforth, Robert D.
author_sort Hamza, Ameer
collection PubMed
description Morquio syndrome is a rare lysosomal storage disease that affects multiple organ systems. However, it is rarely associated with malignancy. We present the case of a 30-year old man with Morquio syndrome associated with gastric adenocarcinoma. This case also demonstrates two other findings that have not been previously described in patients with Morquio syndrome - malrotation of brainstem and cerebellum, without clinical neurologic deficit, and persistence of fetal lobulation in the kidneys.
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spelling pubmed-55075642017-07-24 A second reported malignancy in a patient with Morquio syndrome Hamza, Ameer Khawar, Sidrah Ibrahim, Ahmad Edens, Jacob Lalonde, Crystal Danforth, Robert D. Autops Case Rep Article / Autopsy Case Report Morquio syndrome is a rare lysosomal storage disease that affects multiple organ systems. However, it is rarely associated with malignancy. We present the case of a 30-year old man with Morquio syndrome associated with gastric adenocarcinoma. This case also demonstrates two other findings that have not been previously described in patients with Morquio syndrome - malrotation of brainstem and cerebellum, without clinical neurologic deficit, and persistence of fetal lobulation in the kidneys. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017-06-30 /pmc/articles/PMC5507564/ /pubmed/28740834 http://dx.doi.org/10.4322/acr.2017.019 Text en Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2017. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the article is properly cited.
spellingShingle Article / Autopsy Case Report
Hamza, Ameer
Khawar, Sidrah
Ibrahim, Ahmad
Edens, Jacob
Lalonde, Crystal
Danforth, Robert D.
A second reported malignancy in a patient with Morquio syndrome
title A second reported malignancy in a patient with Morquio syndrome
title_full A second reported malignancy in a patient with Morquio syndrome
title_fullStr A second reported malignancy in a patient with Morquio syndrome
title_full_unstemmed A second reported malignancy in a patient with Morquio syndrome
title_short A second reported malignancy in a patient with Morquio syndrome
title_sort second reported malignancy in a patient with morquio syndrome
topic Article / Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507564/
https://www.ncbi.nlm.nih.gov/pubmed/28740834
http://dx.doi.org/10.4322/acr.2017.019
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