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Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants

Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential molecular process of infection, the precise interactio...

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Detalles Bibliográficos
Autores principales: Sokoloski, Kevin J., Nease, Lauren M., May, Nicholas A., Gebhart, Natasha N., Jones, Claire E., Morrison, Thomas E., Hardy, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507600/
https://www.ncbi.nlm.nih.gov/pubmed/28662211
http://dx.doi.org/10.1371/journal.ppat.1006473