High frequency of intestinal T(H)17 cells correlates with microbiota alterations and disease activity in multiple sclerosis

T helper 17 (T(H)17) cells are key players in multiple sclerosis (MS), and studies in animal models demonstrated that effector T(H)17 cells that trigger brain autoimmunity originate in the intestine. We validate in humans the crucial role of the intestinal environment in promoting T(H)17 cell expans...

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Detalles Bibliográficos
Autores principales: Cosorich, Ilaria, Dalla-Costa, Gloria, Sorini, Chiara, Ferrarese, Roberto, Messina, Maria Josè, Dolpady, Jayashree, Radice, Elisa, Mariani, Alberto, Testoni, Pier Alberto, Canducci, Filippo, Comi, Giancarlo, Martinelli, Vittorio, Falcone, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507635/
https://www.ncbi.nlm.nih.gov/pubmed/28706993
http://dx.doi.org/10.1126/sciadv.1700492

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