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Protein kinase C beta II upregulates intercellular adhesion molecule-1 via mitochondrial activation in cultured endothelial cells

Activation of protein kinase C (PKC) is closely linked with endothelial dysfunction. However, the effect of PKCβII on endothelial dysfunction has not been characterized in cultured endothelial cells. Here, using adenoviral PKCβII gene transfer and pharmacological inhibitors, the role of PKCβII on en...

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Detalles Bibliográficos
Autores principales: Joo, Hee Kyoung, Lee, Yu Ran, Choi, Sunga, Park, Myoung Soo, Kang, Gun, Kim, Cuk-Seong, Jeon, Byeong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507776/
https://www.ncbi.nlm.nih.gov/pubmed/28706451
http://dx.doi.org/10.4196/kjpp.2017.21.4.377