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Participation of COX-1 and COX-2 in the contractile effect of phenylephrine in prepubescent and old rats

Vascular reactivity can be influenced by the vascular region, animal age, and pathologies present. Prostaglandins (produced by COX-1 and COX-2) play an important role in the contractile response to phenylephrine in the abdominal aorta of young rats. Although these COXs are found in many tissues, the...

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Detalles Bibliográficos
Autores principales: Guevara-Balcazar, Gustavo, Ramirez-Sanchez, Israel, Mera-Jimenez, Elvia, Rubio-Gayosso, Ivan, Aguilar-Najera, Maria Eugenia, Castillo-Hernandez, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507779/
https://www.ncbi.nlm.nih.gov/pubmed/28706454
http://dx.doi.org/10.4196/kjpp.2017.21.4.407

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