Steroidal Saponins from the Genus Smilax and Their Biological Activities

ABSTRACT: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with...

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Detalles Bibliográficos
Autores principales: Tian, Li-Wen, Zhang, Zhen, Long, Hai-Lan, Zhang, Ying-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507813/
https://www.ncbi.nlm.nih.gov/pubmed/28646341
http://dx.doi.org/10.1007/s13659-017-0139-5
Descripción
Sumario:ABSTRACT: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins (1–104) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed. GRAPHICAL ABSTRACT: [Image: see text]

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