Steroidal Saponins from the Genus Smilax and Their Biological Activities

ABSTRACT: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with...

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Detalles Bibliográficos
Autores principales: Tian, Li-Wen, Zhang, Zhen, Long, Hai-Lan, Zhang, Ying-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507813/
https://www.ncbi.nlm.nih.gov/pubmed/28646341
http://dx.doi.org/10.1007/s13659-017-0139-5
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author Tian, Li-Wen
Zhang, Zhen
Long, Hai-Lan
Zhang, Ying-Jun
author_facet Tian, Li-Wen
Zhang, Zhen
Long, Hai-Lan
Zhang, Ying-Jun
author_sort Tian, Li-Wen
collection PubMed
description ABSTRACT: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins (1–104) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-55078132017-07-27 Steroidal Saponins from the Genus Smilax and Their Biological Activities Tian, Li-Wen Zhang, Zhen Long, Hai-Lan Zhang, Ying-Jun Nat Prod Bioprospect Review ABSTRACT: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins (1–104) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed. GRAPHICAL ABSTRACT: [Image: see text] Springer Singapore 2017-06-23 /pmc/articles/PMC5507813/ /pubmed/28646341 http://dx.doi.org/10.1007/s13659-017-0139-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Tian, Li-Wen
Zhang, Zhen
Long, Hai-Lan
Zhang, Ying-Jun
Steroidal Saponins from the Genus Smilax and Their Biological Activities
title Steroidal Saponins from the Genus Smilax and Their Biological Activities
title_full Steroidal Saponins from the Genus Smilax and Their Biological Activities
title_fullStr Steroidal Saponins from the Genus Smilax and Their Biological Activities
title_full_unstemmed Steroidal Saponins from the Genus Smilax and Their Biological Activities
title_short Steroidal Saponins from the Genus Smilax and Their Biological Activities
title_sort steroidal saponins from the genus smilax and their biological activities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507813/
https://www.ncbi.nlm.nih.gov/pubmed/28646341
http://dx.doi.org/10.1007/s13659-017-0139-5
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