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Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119(+) erythroblasts were greatly decr...

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Detalles Bibliográficos
Autores principales: Takagishi, Teruhisa, Takehara, Masaya, Seike, Soshi, Miyamoto, Kazuaki, Kobayashi, Keiko, Nagahama, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507896/
https://www.ncbi.nlm.nih.gov/pubmed/28701754
http://dx.doi.org/10.1038/s41598-017-05567-8