Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release

Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-inf...

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Detalles Bibliográficos
Autores principales: Pallavicini, Piersandro, Bassi, Barbara, Chirico, Giuseppe, Collini, Maddalena, Dacarro, Giacomo, Fratini, Emiliano, Grisoli, Pietro, Patrini, Maddalena, Sironi, Laura, Taglietti, Angelo, Moritz, Marcel, Sorzabal-Bellido, Ioritz, Susarrey-Arce, Arturo, Latter, Edward, Beckett, Alison J., Prior, Ian A., Raval, Rasmita, Diaz Fernandez, Yuri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507905/
https://www.ncbi.nlm.nih.gov/pubmed/28701753
http://dx.doi.org/10.1038/s41598-017-05693-3
Descripción
Sumario:Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.

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