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A Robust Method for Inferring Network Structures

Inferring the network structure from limited observable data is significant in molecular biology, communication and many other areas. It is challenging, primarily because the observable data are sparse, finite and noisy. The development of machine learning and network structure study provides a grea...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Luo, Tingjin, Li, Zhoujun, Zhang, Xiaoming, Yu, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507908/
https://www.ncbi.nlm.nih.gov/pubmed/28701799
http://dx.doi.org/10.1038/s41598-017-04725-2
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author Yang, Yang
Luo, Tingjin
Li, Zhoujun
Zhang, Xiaoming
Yu, Philip S.
author_facet Yang, Yang
Luo, Tingjin
Li, Zhoujun
Zhang, Xiaoming
Yu, Philip S.
author_sort Yang, Yang
collection PubMed
description Inferring the network structure from limited observable data is significant in molecular biology, communication and many other areas. It is challenging, primarily because the observable data are sparse, finite and noisy. The development of machine learning and network structure study provides a great chance to solve the problem. In this paper, we propose an iterative smoothing algorithm with structure sparsity (ISSS) method. The elastic penalty in the model is introduced for the sparse solution, identifying group features and avoiding over-fitting, and the total variation (TV) penalty in the model can effectively utilize the structure information to identify the neighborhood of the vertices. Due to the non-smoothness of the elastic and structural TV penalties, an efficient algorithm with the Nesterov’s smoothing optimization technique is proposed to solve the non-smooth problem. The experimental results on both synthetic and real-world networks show that the proposed model is robust against insufficient data and high noise. In addition, we investigate many factors that play important roles in identifying the performance of ISSS.
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spelling pubmed-55079082017-07-14 A Robust Method for Inferring Network Structures Yang, Yang Luo, Tingjin Li, Zhoujun Zhang, Xiaoming Yu, Philip S. Sci Rep Article Inferring the network structure from limited observable data is significant in molecular biology, communication and many other areas. It is challenging, primarily because the observable data are sparse, finite and noisy. The development of machine learning and network structure study provides a great chance to solve the problem. In this paper, we propose an iterative smoothing algorithm with structure sparsity (ISSS) method. The elastic penalty in the model is introduced for the sparse solution, identifying group features and avoiding over-fitting, and the total variation (TV) penalty in the model can effectively utilize the structure information to identify the neighborhood of the vertices. Due to the non-smoothness of the elastic and structural TV penalties, an efficient algorithm with the Nesterov’s smoothing optimization technique is proposed to solve the non-smooth problem. The experimental results on both synthetic and real-world networks show that the proposed model is robust against insufficient data and high noise. In addition, we investigate many factors that play important roles in identifying the performance of ISSS. Nature Publishing Group UK 2017-07-12 /pmc/articles/PMC5507908/ /pubmed/28701799 http://dx.doi.org/10.1038/s41598-017-04725-2 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Yang, Yang
Luo, Tingjin
Li, Zhoujun
Zhang, Xiaoming
Yu, Philip S.
A Robust Method for Inferring Network Structures
title A Robust Method for Inferring Network Structures
title_full A Robust Method for Inferring Network Structures
title_fullStr A Robust Method for Inferring Network Structures
title_full_unstemmed A Robust Method for Inferring Network Structures
title_short A Robust Method for Inferring Network Structures
title_sort robust method for inferring network structures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507908/
https://www.ncbi.nlm.nih.gov/pubmed/28701799
http://dx.doi.org/10.1038/s41598-017-04725-2
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