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Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis

Cystic fibrosis transmembrane conductance regulator (CFTR), known as a cAMP-activated Cl(−) channel, is widely expressed at the apical membrane of epithelial cells in a wide variety of tissues. Of note, despite the abundant expression of CFTR in mammalian kidney, the role of CFTR in kidney disease d...

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Detalles Bibliográficos
Autores principales:	Zhang, Jie Ting, Wang, Yan, Chen, Jun Jiang, Zhang, Xiao Hu, Dong, Jian Da, Tsang, Lai Ling, Huang, Xiao Ru, Cai, Zhiming, Lan, Hui Yao, Jiang, Xiao Hua, Chan, Hsiao Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507915/ https://www.ncbi.nlm.nih.gov/pubmed/28701694 http://dx.doi.org/10.1038/s41598-017-05435-5

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