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Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI

SR-BI is the main receptor for high density lipoproteins (HDL) and mediates the bidirectional transport of lipids, such as cholesterol and vitamin E, between these particles and cells. During early development, SR-BI is expressed in extraembryonic tissue, specifically in trophoblast giant cells in t...

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Detalles Bibliográficos
Autores principales: Santander, Nicolás, Lizama, Carlos, Parga, María José, Quiroz, Alonso, Pérez, Druso, Echeverría, Guadalupe, Ulloa, Lorena, Palma, Verónica, Rigotti, Attilio, Busso, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507922/
https://www.ncbi.nlm.nih.gov/pubmed/28701710
http://dx.doi.org/10.1038/s41598-017-05422-w