Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold

Cysteine-rich peptides (CRPs) of 2–6 kDa are generally thermally and proteolytically stable because of their multiple cross-bracing disulfide bonds. Here, we report the discovery and characterization of two novel cystine-stapled CRPs, designated lybatide 1 and 2 (lyba1 and lyba2), from the cortex of...

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Detalles Bibliográficos
Autores principales: Tan, Wei Liang, Wong, Ka H., Lei, Jian, Sakai, Naoki, Tan, Hong Wei, Hilgenfeld, Rolf, Tam, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507927/
https://www.ncbi.nlm.nih.gov/pubmed/28701689
http://dx.doi.org/10.1038/s41598-017-05037-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507927/
https://www.ncbi.nlm.nih.gov/pubmed/28701689
http://dx.doi.org/10.1038/s41598-017-05037-1

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