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Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold
Cysteine-rich peptides (CRPs) of 2–6 kDa are generally thermally and proteolytically stable because of their multiple cross-bracing disulfide bonds. Here, we report the discovery and characterization of two novel cystine-stapled CRPs, designated lybatide 1 and 2 (lyba1 and lyba2), from the cortex of...
Autores principales: | Tan, Wei Liang, Wong, Ka H., Lei, Jian, Sakai, Naoki, Tan, Hong Wei, Hilgenfeld, Rolf, Tam, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507927/ https://www.ncbi.nlm.nih.gov/pubmed/28701689 http://dx.doi.org/10.1038/s41598-017-05037-1 |
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