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Patients Lacking a KIR-Ligand of HLA Group C1 or C2 Have a Better Outcome after Umbilical Cord Blood Transplantation

Donor natural killer (NK) cells can destroy residual leukemic cells after allogeneic hematopoietic stem cell transplantation. This effect is based on the interaction of killer-cell immunoglobulin-like receptors (KIR) of donor NK cells with ligands of the major histocompatibility complex found on the...

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Detalles Bibliográficos
Autores principales: Martínez-Losada, Carmen, Martín, Carmen, Gonzalez, Rafael, Manzanares, Bárbara, García-Torres, Estefania, Herrera, Concha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507950/
https://www.ncbi.nlm.nih.gov/pubmed/28751893
http://dx.doi.org/10.3389/fimmu.2017.00810