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Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation

Aim: Effective treatment of premature infants with bronchopulmonary dysplasia (BPD) is lacking. We hypothesize that bone morphogenetic protein 9 (BMP9), a ligand of the TGF-β family that binds to the activin receptor-like kinase 1 (ALK1)-BMP receptor type 2 (BMPR2) receptor complex, may be a novel t...

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Detalles Bibliográficos
Autores principales: Chen, Xueyu, Orriols, Mar, Walther, Frans J., Laghmani, El Houari, Hoogeboom, Annemarie M., Hogen-Esch, Anne C. B., Hiemstra, Pieter S., Folkerts, Gert, Goumans, Marie-José T. H., ten Dijke, Peter, Morrell, Nicholas W., Wagenaar, Gerry T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507999/
https://www.ncbi.nlm.nih.gov/pubmed/28751863
http://dx.doi.org/10.3389/fphys.2017.00486