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The BDNF val-66-met Polymorphism Affects Neuronal Morphology and Synaptic Transmission in Cultured Hippocampal Neurons from Rett Syndrome Mice

Brain-derived neurotrophic factor (Bdnf) has been implicated in several neurological disorders including Rett syndrome (RTT), an X-linked neurodevelopmental disorder caused by loss-of-function mutations in the transcriptional modulator methyl-CpG-binding protein 2 (MECP2). The human BDNF gene has a...

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Detalles Bibliográficos
Autores principales:	Xu, Xin, Garcia, Jordi, Ewalt, Rachel, Nason, Shelly, Pozzo-Miller, Lucas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508027/ https://www.ncbi.nlm.nih.gov/pubmed/28751857 http://dx.doi.org/10.3389/fncel.2017.00203

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