Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia

Children with P2RY8-CRLF2-positive acute lymphoblastic leukemia have an increased relapse risk. Their mutational and transcriptional landscape, as well as the respective patterns at relapse remain largely elusive. We, therefore, performed an integrated analysis of whole-exome and RNA sequencing in 4...

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Detalles Bibliográficos
Autores principales: Vesely, C, Frech, C, Eckert, C, Cario, G, Mecklenbräuker, A, zur Stadt, U, Nebral, K, Kraler, F, Fischer, S, Attarbaschi, A, Schuster, M, Bock, C, Cavé, H, von Stackelberg, A, Schrappe, M, Horstmann, M A, Mann, G, Haas, O A, Panzer-Grümayer, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508072/
https://www.ncbi.nlm.nih.gov/pubmed/27899802
http://dx.doi.org/10.1038/leu.2016.365

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