Cargando…

Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma

Genetically engineered mouse models that employ site-specific recombinase technology are important tools for cancer research but can be costly and time-consuming. The CRISPR-Cas9 system has been adapted to generate autochthonous tumours in mice, but how these tumours compare to tumours generated by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jianguo, Chen, Mark, Whitley, Melodi Javid, Kuo, Hsuan-Cheng, Xu, Eric S., Walens, Andrea, Mowery, Yvonne M., Van Mater, David, Eward, William C., Cardona, Diana M., Luo, Lixia, Ma, Yan, Lopez, Omar M., Nelson, Christopher E., Robinson-Hamm, Jacqueline N., Reddy, Anupama, Dave, Sandeep S., Gersbach, Charles A., Dodd, Rebecca D., Kirsch, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508130/ https://www.ncbi.nlm.nih.gov/pubmed/28691711 http://dx.doi.org/10.1038/ncomms15999

Ejemplares similares

Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 systems
por: Liu, Hualan, et al.
Publicado: (2020)

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous Kras(G12D)
por: Huang, Jianguo, et al.
Publicado: (2019)

Targeted genome and epigenome editing using engineered TALE and CRISPR/Cas9 technologies
por: Gersbach, Charles A
Publicado: (2014)

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
por: Kabadi, Ami M., et al.
Publicado: (2014)

A light-inducible CRISPR/Cas9 system for control of endogenous gene activation
por: Polstein, Lauren R., et al.
Publicado: (2015)

Generation of CRISPR/Cas9-mediated bicistronic knock-in ins1-cre driver mice
por: Hasegawa, Yoshikazu, et al.
Publicado: (2016)

A Cre-Dependent CRISPR/dCas9 System for Gene Expression Regulation in Neurons
por: Carullo, Nancy V. N., et al.
Publicado: (2021)

Generation of scalable cancer models by combining AAV-intron-trap, CRISPR/Cas9, and inducible Cre-recombinase
por: Boddu, Prajwal C., et al.
Publicado: (2021)

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting
por: Ackermann, Amanda M., et al.
Publicado: (2017)

A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma
por: Lazarides, Alexander L., et al.
Publicado: (2016)

Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration
por: Almeida, Maira P., et al.
Publicado: (2021)

MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma
por: Sachdeva, Mohit, et al.
Publicado: (2015)

A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification
por: Chakraborty, Syandan, et al.
Publicado: (2014)

Painful Foot Lesions: A Case Report
por: Lockard, Trevor J, et al.
Publicado: (2023)

Generation of a conditional mutant knock-in under the control of the natural promoter using CRISPR-Cas9 and Cre-Lox systems
por: Thakur, Vijay S., et al.
Publicado: (2020)

Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration
por: Liu, Fang, et al.
Publicado: (2022)

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy
por: Ousterout, David G., et al.
Publicado: (2015)

Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators
por: Kwon, Jennifer B., et al.
Publicado: (2020)

Targeted Chromosomal Rearrangements via Combinatorial Use of CRISPR/Cas9 and Cre/LoxP Technologies in Caenorhabditis elegans
por: Chen, Xiangyang, et al.
Publicado: (2018)

Generation of Marker-Free pbd-2 Knock-in Pigs Using the CRISPR/Cas9 and Cre/loxP Systems
por: Huang, Jing, et al.
Publicado: (2020)

Wobble Editing of Cre-box by Unspecific CRISPR/Cas9 Causes CCR Release and Phenotypic Changes in Bacillus pumilus
por: Wang, Yingxiang, et al.
Publicado: (2021)

Structured Illumination Microscopy and a Quantitative Image Analysis for the Detection of Positive Margins in a Pre-Clinical Genetically Engineered Mouse Model of Sarcoma
por: Fu, Henry L., et al.
Publicado: (2016)

RNA-guided gene activation by CRISPR-Cas9-based transcription factors
por: Perez-Pinera, Pablo, et al.
Publicado: (2013)

RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
por: Thakore, Pratiksha I., et al.
Publicado: (2018)

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers
por: Hilton, Isaac B., et al.
Publicado: (2015)

Highly Specific Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements
por: Thakore, Pratiksha I., et al.
Publicado: (2015)

A case of trichodysplasia spinulosa related to ruxolitinib treated successfully with oral acitretin
por: Rosa‐Nieves, Priscilla M., et al.
Publicado: (2023)

Hidradenitis Suppurativa: Host-Microbe and Immune Pathogenesis Underlie Important Future Directions
por: Jiang, Simon W., et al.
Publicado: (2021)

A CRISPR/Cas9 and Cre/Lox system-based express vaccine development strategy against re-emerging Pseudorabies virus
por: Liang, Xun, et al.
Publicado: (2016)

Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP
por: Bi, Yanzhen, et al.
Publicado: (2016)

Production of L-Malic Acid by Metabolically Engineered Aspergillus nidulans Based on Efficient CRISPR–Cas9 and Cre-loxP Systems
por: Chen, Ziqing, et al.
Publicado: (2023)

What is CRISPR/Cas9?
por: Redman, Melody, et al.
Publicado: (2016)

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease
por: Gratz, Scott J., et al.
Publicado: (2013)

Papulonecrotic tuberculid and Poncet disease: A case of multisystem delayed-type hypersensitivity in a patient with Mycobacterium tuberculosis infection
por: Whitley, Melodi Javid, et al.
Publicado: (2019)

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells
por: Pickar-Oliver, Adrian, et al.
Publicado: (2019)

The Application of NHEJ-CRISPR/Cas9 and Cre-Lox System in the Generation of Bivalent Duck Enteritis Virus Vaccine against Avian Influenza Virus
por: Chang, Pengxiang, et al.
Publicado: (2018)

Divergent degeneration of creA antitoxin genes from minimal CRISPRs and the convergent strategy of tRNA-sequestering CreT toxins
por: Cheng, Feiyue, et al.
Publicado: (2021)

The generation and characterization of novel Col1a1(FRT-Cre-ER-T2-FRT) and Col1a1(FRT-STOP-FRT-Cre-ER-T2) mice for sequential mutagenesis
por: Zhang, Minsi, et al.
Publicado: (2015)

Retraction: The generation and characterization of novel Col1a1(FRT-Cre-ER-T2-FRT) and Col1a1(FRT-STOP-FRT-Cre-ER-T2) mice for sequential mutagenesis
por: Zhang, Minsi, et al.
Publicado: (2016)

Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination
por: Weidenhammer, Loren B., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3c603urdiluqu20v72v1a1pva3