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Crosstalk and the evolvability of intracellular communication

Metazoan signalling networks are complex, with extensive crosstalk between pathways. It is unclear what pressures drove the evolution of this architecture. We explore the hypothesis that crosstalk allows different cell types, each expressing a specific subset of signalling proteins, to activate diff...

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Detalles Bibliográficos
Autores principales:	Rowland, Michael A., Greenbaum, Joseph M., Deeds, Eric J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508131/ https://www.ncbi.nlm.nih.gov/pubmed/28691706 http://dx.doi.org/10.1038/ncomms16009

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