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Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target
The widespread application of high-throughput sequencing methods is resulting in the identification of a rapidly growing number of novel gene fusions caused by tumour-specific chromosomal rearrangements, whose oncogenic potential remains unknown. Here we describe a strategy that builds upon recent a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508201/ https://www.ncbi.nlm.nih.gov/pubmed/28695888 http://dx.doi.org/10.1038/ncomms15987 |