Acute and long‐term effects of brivaracetam and brivaracetam–diazepam combinations in an experimental model of status epilepticus

OBJECTIVE: To evaluate acute and long‐term effects of intravenous brivaracetam (BRV) and BRV + diazepam (DZP) combination treatment in a rat model of self‐sustaining status epilepticus (SSSE). METHODS: Rats were treated with BRV (10 mg/kg) 10 min after initiation of perforant path stimulation (PPS)...

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Detalles Bibliográficos
Autores principales: Niquet, Jerome, Suchomelova, Lucie, Thompson, Kerry, Klitgaard, Henrik, Matagne, Alain, Wasterlain, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508597/
https://www.ncbi.nlm.nih.gov/pubmed/28597912
http://dx.doi.org/10.1111/epi.13787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508597/
https://www.ncbi.nlm.nih.gov/pubmed/28597912
http://dx.doi.org/10.1111/epi.13787

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