Anti-high mobility group box-1 (HMGB1) antibody attenuates kidney damage following experimental crush injury and the possible role of the tumor necrosis factor-α and c-Jun N-terminal kinase pathway

BACKGROUND: Inflammation plays a crucial role in kidney damage after crush syndrome (CS). Several researchers report that high mobility group box-1 protein (HMGB1) may be the vital trigger in kidney damage, and tumor necrosis factor-α (TNF-α) and c-Jun N-terminal kinase (JNK) are involve in this pat...

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Detalles Bibliográficos
Autores principales: Zhang, Bin-Fei, Wang, Peng-Fei, Cong, Yu-Xuan, Lei, Jin-Lai, Wang, Hu, Huang, Hai, Han, Shuang, Zhuang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508710/
https://www.ncbi.nlm.nih.gov/pubmed/28701229
http://dx.doi.org/10.1186/s13018-017-0614-z

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