Alantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades

BACKGROUND: Glioblastoma multiforme (GBM) is one of the most refractory and palindromic central nervous system (CNS) neoplasms, and current treatments have poor effects in GBM patients. Hence, the identification of novel therapeutic targets and the development of effective treatment strategies are e...

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Detalles Bibliográficos
Autores principales: Wang, Xun, Yu, Zhenlong, Wang, Chao, Cheng, Wei, Tian, Xiangge, Huo, Xiaokui, Wang, Yan, Sun, Chengpeng, Feng, Lei, Xing, Jinshan, Lan, Yulong, Sun, Dongdong, Hou, Qingjuan, Zhang, Baojing, Ma, Xiaochi, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508758/
https://www.ncbi.nlm.nih.gov/pubmed/28701209
http://dx.doi.org/10.1186/s13046-017-0563-8

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