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Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

BACKGROUND: Tuberculosis patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions, such as hepatotoxicity. Genetic risk factors, such as polymorphisms of the NAT2, CYP2E1 and GSTM1 genes, may increase the risk of experiencing such toxicity events. Many pharmacogen...

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Detalles Bibliográficos
Autores principales:	Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek, Davies, Geraint, Jorgensen, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508765/ https://www.ncbi.nlm.nih.gov/pubmed/28701180 http://dx.doi.org/10.1186/s13643-017-0533-4

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