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A (99m)Tc-labelled scFv antibody fragment that binds to prostate-specific membrane antigen

INTRODUCTION: Prostate-specific membrane antigen (PSMA) is an extensively studied antigen for imaging prostate cancer. We prepared a single-chain variable fragment (scFv) of J591, a monoclonal antibody that recognises an external epitope of PSMA, incorporating a His-tag for labelling with (99m)Tc tr...

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Detalles Bibliográficos
Autores principales:	Nawaz, Saima, Mullen, Gregory E.D., Blower, Philip J., Ballinger, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508854/ https://www.ncbi.nlm.nih.gov/pubmed/28598898 http://dx.doi.org/10.1097/MNM.0000000000000698

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