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Susceptibility of Clinical Isolates of Burkholderia pseudomallei to a Lipid A Biosynthesis Inhibitor
Burkholderia pseudomallei is the causative agent of melioidosis, a serious infection associated with high mortality and relapse. Current antimicrobial therapy using ceftazidime (CAZ) is often ineffective. Inhibitors of LpxC, the enzyme responsible for lipid A biosynthesis, have potential antimicrobi...
Autores principales: | Sengyee, Sineenart, Saiprom, Natnaree, Paksanont, Suporn, Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Chantratita, Narisara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508901/ https://www.ncbi.nlm.nih.gov/pubmed/28719324 http://dx.doi.org/10.4269/ajtmh.16-0858 |
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