Cargando…
Low-Molecular-Weight NGF Mimetic Corrects the Cognitive Deficit and Depression-like Behavior in Experimental Diabetes
Based on the comorbidity of diabetes, depression, and dementia and recognizing that a deficiency of the nerve growth factor (NGF) is involved in all of these kinds of pathologies, we studied the effect of the mimetic of dimeric dipeptide NGF loop 4, GK-2, on a model of streptozotocin-induced type 2...
Autores principales: | Ostrovskaya, R. U., Yagubova, S. S., Gudasheva, T. A., Seredenin, S. B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509006/ https://www.ncbi.nlm.nih.gov/pubmed/28740732 |
Ejemplares similares
-
A Novel Dipeptide NGF Mimetic GK-2 Selectively Activating the PI3K/AKT Signaling Pathway Promotes the Survival of Pancreatic β-Cells in a Rat Model of Diabetes
por: Ostrovskaya, R. U., et al.
Publicado: (2019) -
Original Nerve Growth Factor Mimetic Dipeptide GK-2 Restores Impaired Cognitive Functions in Rat Models of Alzheimer’s Disease
por: Povarnina, P.Yu., et al.
Publicado: (2013) -
Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk
por: Mezhlumyan, Armen G., et al.
Publicado: (2022) -
Novel Technologies for Dipeptide Drugs Design and their Implantation
por: Gudasheva, Tatiana A., et al.
Publicado: (2018) -
Antidepressant Effect of an Orally Administered Dipeptide Mimetic of the Brain-Derived Neurotrophic Factor
por: Povarnina, P. Y., et al.
Publicado: (2018)